Stanko C M, Severson M A, Molpus K L
Department of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, USA.
J Reprod Med. 2001 Apr;46(4):405-7.
The association of deep venous thrombosis (DVT) with uterine leiomyomata has been reported only rarely in the English-language literature. These concomitant findings occurred in a woman with no other known risk factors for development of DVT.
A 49-year-old, Caucasian woman, gravida 3, para 3, with a past medical history significant for large uterine leiomyomata, menorrhagia and anemia, presented with acute edema of the left lower extremity. Doppler studies revealed compression of the left iliofemoral vein with associated thrombosis. No risk factors for DVT were identified. Intravenous heparin was initiated, with eventual preoperative placement of an inferior vena cava Greenfield filter. A total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed without complications.
Large uterine leiomyomata are a potential cause of lower extremity venous stasis and resulting thrombosis and can be treated with hysterectomy.
深静脉血栓形成（DVT）与子宫平滑肌瘤的关联在英文文献中仅有极少报道。这些并发情况出现在一名无其他已知DVT发生风险因素的女性身上。
一名49岁的白种女性，孕3产3，既往有大型子宫平滑肌瘤、月经过多和贫血病史，出现左下肢急性水肿。多普勒检查显示左髂股静脉受压并伴有血栓形成。未发现DVT的风险因素。开始静脉注射肝素，最终在术前放置了下腔静脉格林菲尔德滤器。进行了全腹子宫切除术和双侧输卵管卵巢切除术，无并发症。
大型子宫平滑肌瘤是下肢静脉淤滞及由此导致血栓形成的一个潜在原因，可通过子宫切除术进行治疗。
