Podduturi Varsha, Armstrong-Briley Danielle R, Guileyardo Joseph M
Department of Pathology, Baylor University Medical Center, Dallas, TX, USA.
Case Rep Obstet Gynecol. 2014;2014:181265. doi: 10.1155/2014/181265. Epub 2014 Dec 21.
The pathophysiology of venous thrombosis is classically attributed to alterations in one or more components of Virchow's triad: hypercoagulability, stasis, and damage to the vascular endothelium. Deep vein thrombosis (DVT) may lead to pulmonary thromboembolism (PE), and the latter is culpable for many deaths annually in the United States; however, DVT as a complication of uterine leiomyoma has rarely been reported. We report a case of a 57-year-old woman whose death was due to a large pedunculated subserosal leiomyoma externally compressing the pelvic veins resulting in stasis and venous thrombosis leading to fatal PE. The association of large pelvic masses with venous thrombosis has clinical implications, since prophylactic surgery could be life-saving.
高凝状态、血流淤滞和血管内皮损伤。深静脉血栓形成（DVT）可能导致肺血栓栓塞症（PE），在美国，后者每年导致许多人死亡；然而，DVT作为子宫平滑肌瘤的并发症鲜有报道。我们报告一例57岁女性病例，其死亡原因是一个带蒂的浆膜下大平滑肌瘤从外部压迫盆腔静脉，导致血流淤滞和静脉血栓形成，进而引发致命的PE。盆腔大肿块与静脉血栓形成之间的关联具有临床意义，因为预防性手术可能挽救生命。
