Chiu J H, Wong K S, Hsia S H, Lai S H
Department of Pediatrics, Li-Shin Hospital, Taoyuan, Taiwan.
Acta Paediatr Taiwan. 2001 Mar-Apr;42(2):101-4.
Idiopathic pulmonary hemosiderosis (IPH) is uncommon in children. We report a 3-year-old girl who was presented with acute pale-looking appearance, hemoptysis, hematemesis and shortness of breath. This patient was confirmed to have pulmonary hemorrhage by the presence of hemosiderin-laden macrophages in the bronchoalveolar lavage fluid using a flexible bronchoscope. Other causes of PH including glomerular, cardiac and immunological disorder were excluded by normal laboratory studies. She was primarily treated by oral prednisolone, but due to recurrent hemoptysis, immunosuppressive agent was added for maintenance therapy. Pediatricians should consider PH in a patient who has recurrent dyspnea, hemoptysis and iron deficiency anemia.
特发性肺含铁血黄素沉着症(IPH)在儿童中并不常见。我们报告一名3岁女孩,她出现急性面色苍白、咯血、呕血和呼吸急促。通过使用可弯曲支气管镜在支气管肺泡灌洗液中发现含铁血黄素巨噬细胞,证实该患者有肺出血。通过正常实验室检查排除了包括肾小球、心脏和免疫性疾病在内的其他肺出血原因。她最初接受口服泼尼松龙治疗,但由于反复咯血,添加了免疫抑制剂进行维持治疗。儿科医生在遇到反复出现呼吸困难、咯血和缺铁性贫血的患者时应考虑肺出血。