Gawlak-Prycka A
Klinika Otolaryngologii AM w Poznaniu.
Otolaryngol Pol. 2001;55(1):35-41.
In the ENT Dept K. Marcinkowski University of Medical Sciences in Poznań between 1984-1998 2145 laryngectomies were performed (710 partial and 1435 total). 192 samples of macroscopically changed tissues were collected from prelaryngeal area during operations. On the basis of histological examination there were 24 cases of lymph nodes with neoplastic metastases and 132 cases lymph nodes without changes or with inflammatory changes. Relapse of tumor during two years after the operations was found in 15/24 (62.4%) in the group with positive Delphian lymph node. In the group with lymph node without changes, relapse of tumor was found in 23/132 (17.4%) patients. In the group with positive Delphian node in 8 cases, metastases were found also in lateral lymph nodes of the neck. In 75% cases (6/8) relapse of tumor was observed. The frequency of relapse was statistically higher in patients with a positive Delphian node. The presence of metastases in prelaryngeal lymph node is a significant unfavourable prognostic factor.
1984年至1998年间，在波兹南的K. 马尔钦科夫斯基医科大学耳鼻喉科进行了2145例喉切除术（710例部分喉切除术和1435例全喉切除术）。手术期间从喉前区域采集了192份肉眼可见病变组织样本。根据组织学检查，有24例淋巴结出现肿瘤转移，132例淋巴结无变化或有炎症变化。在Delphian淋巴结阳性组中，15/24（62.4%）的患者在术后两年内出现肿瘤复发。在淋巴结无变化组中，23/132（17.4%）的患者出现肿瘤复发。在Delphian淋巴结阳性组中，有8例患者在颈部外侧淋巴结也发现了转移。在75%（6/8）的病例中观察到肿瘤复发。Delphian淋巴结阳性患者的复发频率在统计学上更高。喉前淋巴结转移的存在是一个显著的不良预后因素。
