前哨淋巴结活检时代淋巴结阳性黑色素瘤的管理
Management of node-positive melanoma in the era of sentinel node biopsy.
作者信息
White R R, Tyler D S
机构信息
Department of Surgery, Duke University Medical Center, Box 3118, 27710, Durham, NC, USA.
出版信息
Surg Oncol. 2000 Nov;9(3):119-25. doi: 10.1016/s0960-7404(00)00042-6.
Regional lymph node metastasis is a powerful predictor of decreased overall survival from malignant melanoma. However, the therapeutic value of elective node dissections and the role of adjuvant therapy for node-positive disease have been highly controversial. Sentinel lymph node biopsy has reshaped the debate by allowing for staging of the regional lymph nodes with less morbidity and greater accuracy. This review summarizes the current consensus on the management of node-positive melanoma in the era of sentinel lymph node biopsy.
区域淋巴结转移是恶性黑色素瘤总体生存率降低的有力预测指标。然而，选择性淋巴结清扫术的治疗价值以及辅助治疗对淋巴结阳性疾病的作用一直存在高度争议。前哨淋巴结活检通过以较低的发病率和更高的准确性对区域淋巴结进行分期，重塑了这场争论。本综述总结了在前哨淋巴结活检时代关于淋巴结阳性黑色素瘤管理的当前共识。
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