Laffon E, Laurent F, Bernard V, De Boucaud L, Ducassou D, Marthan R
Service de Médecine Nucléaire, Hôpital du Haut-Lévêque, 33604 Pessac, France.
J Appl Physiol (1985). 2001 Jun;90(6):2197-202. doi: 10.1152/jappl.2001.90.6.2197.
We describe a magnetic resonance (MR) imaging method that emphasizes pressure wave velocity to noninvasively assess pulmonary arterial hypertension. Both the blood flow and the corresponding vessel cross-sectional area (CSA) were measured by MR phase mapping in the main pulmonary artery (MPA) in 15 patients. MPA pressures were also measured, in the same patients, by right-side heart catheterization. Two significant relationships were established: 1) between the pressure wave velocity in the MPA and the mean pressure in the MPA (Ppa) writing pressure wave velocity = 9.25 Ppa - 202.51 (r = 0.82) and 2) between the ratio of pressure wave velocity to the systolic blood velocity peak in the MPA (R) and the mean pressure in the MPA writing R = 0.68 Ppa - 4.33 (r = 0.89). Using these relationships, we estimated two pressure values to frame the actual Ppa value in each patient from the present series with a reasonable reliability percentage (87%).
我们描述了一种磁共振（MR）成像方法，该方法通过强调压力波速度来无创评估肺动脉高压。对15例患者的主肺动脉（MPA）进行MR相位成像，测量血流和相应的血管横截面积（CSA）。同时，通过右侧心导管插入术测量同一批患者的MPA压力。建立了两个显著的关系：1）MPA中的压力波速度与MPA中的平均压力（Ppa）之间的关系，即压力波速度=9.25Ppa - 202.51（r = 0.82）；2）MPA中压力波速度与收缩期血流速度峰值之比（R）与MPA中的平均压力之间的关系，即R = 0.68Ppa - 4.33（r = 0.89）。利用这些关系，我们从本系列的每位患者中估计出两个压力值，以合理的可靠率（87%）确定实际的Ppa值。
