Calista D, Schianchi S, Morri M
Department of Dermatology, M.Bufalini Hospital, Cesena, Italy.
Pediatr Dermatol. 2001 Mar-Apr;18(2):114-6. doi: 10.1046/j.1525-1470.2001.018002114.x.
A 5-year-old girl presented with a 2-week history of a sharply demarcated, inflammatory, granulomatous lesion on the right side of her scalp. Shortly afterward, painful, subcutaneous nodules developed on her shins and thighs. Trichophyton mentagrophytes was isolated from the scalp lesion and a diagnosis of erythema nodosum induced by kerion of the scalp was made. The patient was started on oral therapy with 18 mg/kg/day griseofulvin, associated with topical crystal violet. Her erythema nodosum regressed in 10 days, while the kerion healed 6 weeks later, leaving residual scarring alopecia. Erythema nodosum represents a reaction pattern to a wide variety of inflammatory stimuli. The interest of this case lies in the unusual association of kerion erythema nodosum, of which only nine cases have been reported in the international literature.
一名5岁女孩,头皮右侧出现界限清晰的炎症性肉芽肿病变,病程2周。不久后,她的小腿和大腿出现疼痛性皮下结节。从头皮病变中分离出须癣毛癣菌,诊断为头皮脓癣诱发的结节性红斑。患者开始口服灰黄霉素,剂量为18mg/kg/天,并外用结晶紫。她的结节性红斑在10天内消退,而脓癣在6周后愈合,留下残余瘢痕性脱发。结节性红斑是对多种炎症刺激的一种反应模式。该病例的有趣之处在于脓癣结节性红斑这种不寻常的关联,国际文献中仅报道过9例。