Mycoses. 2011 Jul;54(4):e237-9. doi: 10.1111/j.1439-0507.2009.01844.x. Epub 2010 Jan 22.
A 35-year-old woman, with a 3-week history of an enlarging erythematous, scaly plaque of the scalp vertex associated with the onset of some painful, subcutaneous nodules on her pretibial regions. Trichophyton mentagrophytes was isolated from the scalp lesion and the histological examination of one of the nodular lesions of the legs showed a septal panniculitis. The diagnosis of erythema nodosum (EN) induced by kerion celsi was made and the patient started therapy with oral terbinafine 250 mg per day for 4 weeks associated with naproxene per os 1 g per day for 2 weeks. Erythema nodosum is considered a reaction pattern to a wide variety of microbial and non-microbial stimuli: dermatophytic infections are rarely associated with EN.
一位 35 岁女性,3 周前头皮顶点出现红斑、鳞屑性斑块逐渐增大,同时小腿出现一些疼痛的皮下结节。从头皮皮损处分离出须癣毛癣菌,腿部结节性皮损的组织学检查显示间隔性脂膜炎。诊断为由假性化脓性毛囊炎引起的结节性红斑,患者开始接受治疗,每天口服特比萘芬 250mg,持续 4 周,同时每天口服萘普生 1g,持续 2 周。结节性红斑被认为是对各种微生物和非微生物刺激的反应模式:皮肤癣菌感染很少与结节性红斑有关。