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硝唑尼特成功治疗一名获得性免疫缺陷综合征患者的甲硝唑和阿苯达唑耐药贾第虫病。

Successful treatment of metronidazole- and albendazole-resistant giardiasis with nitazoxanide in a patient with acquired immunodeficiency syndrome.

作者信息

Abboud P, Lemée V, Gargala G, Brasseur P, Ballet J J, Borsa-Lebas F, Caron F, Favennec L

机构信息

Service de Maladies Infectieuses, Centre Hospitalier Universitaire Ch. Nicolle, Rouen, France.

出版信息

Clin Infect Dis. 2001 Jun 15;32(12):1792-4. doi: 10.1086/320751. Epub 2001 May 9.

DOI:10.1086/320751
PMID:11360222
Abstract

A case of metronidazole- and albendazole-resistant giardiasis in a patient with the acquired immunodeficiency syndrome was successfully treated with nitazoxanide (1.5 g twice a day for 30 days). Animal studies and in vitro assays showed that the isolate was resistant to both metronidazole and albendazole and susceptible to nitazoxanide.

摘要

一名获得性免疫缺陷综合征患者的甲硝唑和阿苯达唑耐药贾第虫病病例，使用硝唑尼特成功治愈（每天两次，每次1.5克，共30天）。动物研究和体外试验表明，该分离株对甲硝唑和阿苯达唑均耐药，但对硝唑尼特敏感。

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