McCracken J D
West J Med. 1975 Jun;122(6):459-63.
Over a one-year period, 167 patients with cancer were seen in a total of 1,931 clinic visits. Of these patients, 59 percent responded to therapy, with 20 percent achieving a complete response. The median duration of response was eight months (12+ months for complete responders, 7 months for partial responders), with only a two-month average survival for nonresponders. Seventy-seven deaths in clinic patients occurred for a death rate of 46 percent. Hospital tumor registry referrals rose 46 percent. The effect of early referrals, sources of referral, metastatic sites, chemotherapeutic drugs used, morbidity and type of therapy are also reviewed.
在一年时间里,共1931次门诊接诊了167例癌症患者。在这些患者中,59%对治疗有反应,其中20%达到完全缓解。反应的中位持续时间为8个月(完全缓解者为12个多月,部分缓解者为7个月),无反应者的平均生存期仅为2个月。门诊患者中有77例死亡,死亡率为46%。医院肿瘤登记处的转诊量增加了46%。还回顾了早期转诊的影响、转诊来源、转移部位、所用化疗药物、发病率和治疗类型。