Peng Y J, Gong Q L, Li P
Department of Physiology, Shanghai Medical University, Shanghai 200032.
Sheng Li Xue Bao. 1998 Oct;50(5):575-80.
Extracellular recordings were made in nucleus paragigantocellularis lateralis (PGL) of the rat in response to stimulation of the dorsal periaqueductoral gray matter (dPAG), ventrolateral periaqueductuctoral gray matter (vPAG), deep peroneal nerve (DPN), median nerve (MN) and great splanchnic nerve (GSPL). Stimulation of dPAG or MN evoked mainly excitatory responses while the responses to stimulation of vPAG were inhibitory. However, stimulation of GSPL or DPN produced both inhibitory and excitatory responses. These neurons were not only responsive to one stimulation site, but were likely responsive to any other stimulation sites. Eighty-nine percent of cells tested (73/82) received convergent inputs from two or more sites. Sixty percent (21/35) of the neurons were identified as cardiovascular units based on their barosensitivity and slow conduction velocities of the descending axons projecting into the spinal cord. This result provided new evidence for the integrative function of neurons in PGL under some circumstances.
在大鼠外侧巨细胞旁核（PGL）进行细胞外记录，以响应背侧导水管周围灰质（dPAG）、腹外侧导水管周围灰质（vPAG）、腓深神经（DPN）、正中神经（MN）和内脏大神经（GSPL）的刺激。刺激dPAG或MN主要引起兴奋性反应，而刺激vPAG则产生抑制性反应。然而，刺激GSPL或DPN会产生抑制性和兴奋性反应。这些神经元不仅对一个刺激位点有反应，而且可能对任何其他刺激位点都有反应。89%（73/82）的测试细胞接受来自两个或更多位点的汇聚输入。根据其压力敏感性和投射到脊髓的下行轴突的慢传导速度，60%（21/35）的神经元被确定为心血管单位。这一结果为某些情况下PGL中神经元的整合功能提供了新证据。
