Atanackovic G, Wolpin J, Koren G
Department of Pediatrics and Research Institute, The Hospital for Sick Children, Toronto, Ont.
Clin Invest Med. 2001 Apr;24(2):90-3.
To characterize a cohort of pregnant women who required hospital care owing to nausea and vomiting of pregnancy (NVP) and to identify variables that could serve as predictors of the need for hospital care.
A retrospective, observational study.
Between 1996 and 1997, women who suffered from NVP were invited to call the NVP Healthline at The Motherisk Program in Toronto. After obtaining verbal consent, callers were interviewed by trained counsellors through a structured questionnaire about their NVP experience in previous pregnancies. Univariate and multivariate analyses were used to identify factors that could predict the need for hospital care.
In total, 3,201 women were recruited;1,348 (43.8%) needed hospital care (treatment in the emergency room, day unit or hospital ward). The following characteristics were significantly associated with the need for hospital care: severity of vomiting (more than 5 times a day), use of more than one antiemetic medication, being primigravid, feeling depressed, having had an obstetrician as the primary health care provider and feeling that NVP had affected the partner's daily life.
Several factors, including the severity of physical symptoms of NVP and psychosocial factors, are associated with the need for hospital care. In addition to treatment of physical symptoms, it is important to address other factors associated with NVP.
对因妊娠恶心和呕吐（NVP）而需要住院治疗的孕妇群体进行特征描述，并确定可作为住院治疗需求预测指标的变量。
一项回顾性观察研究。
1996年至1997年期间，邀请患有NVP的女性拨打多伦多Motherisk项目的NVP健康热线。在获得口头同意后，训练有素的咨询师通过结构化问卷对来电者就其既往妊娠期间的NVP经历进行访谈。采用单因素和多因素分析来确定可预测住院治疗需求的因素。
共招募了3201名女性；1348名（43.8%）需要住院治疗（在急诊室、日间病房或医院病房接受治疗）。以下特征与住院治疗需求显著相关：呕吐严重程度（每天超过5次）、使用不止一种止吐药物、初产妇、感到抑郁、以产科医生作为主要医疗服务提供者以及认为NVP影响了伴侣的日常生活。
包括NVP身体症状严重程度和社会心理因素在内的几个因素与住院治疗需求相关。除了治疗身体症状外，处理与NVP相关的其他因素也很重要。
