Gilmour R S, Mitchell M D
Liggins Institute and Department of Pharmacology & Clinical Pharmacology, University of Auckland, Faculty of Medical and Health Sciences, New Zealand.
Exp Biol Med (Maywood). 2001 Jan;226(1):1-4. doi: 10.1177/153537020122600101.
Nuclear lipid signaling is an established, widespread mechanism that operates in multiple cellular processes including proliferative and differentiative responses to a variety of stimuli. In this literature review with key references highlighted, we put forward the hypothesis that differential flow through various intracrine mechanisms can dictate resultant cellular actions such as mitosis, differentiation, or apoptosis.
核脂质信号传导是一种既定的、广泛存在的机制,它在多种细胞过程中发挥作用,包括对各种刺激的增殖和分化反应。在这篇突出关键参考文献的文献综述中,我们提出一个假说,即通过各种内分泌机制的不同流量可以决定诸如有丝分裂、分化或凋亡等细胞作用结果。