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核脂质信号传导:类花生酸的新作用。

Nuclear lipid signaling: novel role of eicosanoids.

作者信息

Gilmour R S, Mitchell M D

机构信息

Liggins Institute and Department of Pharmacology & Clinical Pharmacology, University of Auckland, Faculty of Medical and Health Sciences, New Zealand.

出版信息

Exp Biol Med (Maywood). 2001 Jan;226(1):1-4. doi: 10.1177/153537020122600101.

DOI:10.1177/153537020122600101
PMID:11368232
Abstract

Nuclear lipid signaling is an established, widespread mechanism that operates in multiple cellular processes including proliferative and differentiative responses to a variety of stimuli. In this literature review with key references highlighted, we put forward the hypothesis that differential flow through various intracrine mechanisms can dictate resultant cellular actions such as mitosis, differentiation, or apoptosis.

摘要

核脂质信号传导是一种既定的、广泛存在的机制,它在多种细胞过程中发挥作用,包括对各种刺激的增殖和分化反应。在这篇突出关键参考文献的文献综述中,我们提出一个假说,即通过各种内分泌机制的不同流量可以决定诸如有丝分裂、分化或凋亡等细胞作用结果。

相似文献

1
Nuclear lipid signaling: novel role of eicosanoids.核脂质信号传导:类花生酸的新作用。
Exp Biol Med (Maywood). 2001 Jan;226(1):1-4. doi: 10.1177/153537020122600101.
2
Lipid mediators in the neural cell nucleus: their metabolism, signaling, and association with neurological disorders.神经细胞核中的脂质介质:它们的代谢、信号传导以及与神经疾病的关联。
Neuroscientist. 2009 Aug;15(4):392-407. doi: 10.1177/1073858409337035.
3
Lipids as bioeffectors in the immune system.脂质作为免疫系统中的生物效应物。
Life Sci. 2005 Aug 19;77(14):1699-710. doi: 10.1016/j.lfs.2005.05.013.
4
Metabolism of arachidonic acid to eicosanoids within the nucleus.花生四烯酸在细胞核内代谢为类二十烷酸。
Biochim Biophys Acta. 2006 May-Jun;1761(5-6):618-25. doi: 10.1016/j.bbalip.2006.02.018. Epub 2006 Mar 20.
5
Eicosanoids and the liver.类二十烷酸与肝脏
Prog Liver Dis. 1990;9:117-41.
6
[Etiological significance of prostaglandins and related substances in hypertension].
Nihon Rinsho. 1992 Apr;50 Suppl:309-17.
7
Phospholipase A2.磷脂酶A2
J Biochem. 2002 Mar;131(3):285-92. doi: 10.1093/oxfordjournals.jbchem.a003101.
8
[Eicosanoids].[类花生酸]
Tanpakushitsu Kakusan Koso. 1990 Mar;35(4 Suppl):546-60.
9
Arachidonic acid cascade and signal transduction.
J Neurochem. 1990 Jul;55(1):1-15. doi: 10.1111/j.1471-4159.1990.tb08813.x.
10
Eicosanoids in prostate cancer.前列腺癌中的类二十烷酸。
Cancer Metastasis Rev. 2018 Sep;37(2-3):237-243. doi: 10.1007/s10555-018-9750-0.

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Homeostatic restitution of cell membranes. Nuclear membrane lipid biogenesis and transport of protein from cytosol to intranuclear spaces.细胞膜的内稳态恢复。核膜脂的生物发生和细胞质中蛋白质向核内空间的转运。
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