Characterization of the t(4;14)(p16.3;q32) in the KMS-18 multiple myeloma cell line.
作者信息
Ronchetti D, Bogni S, Finelli P, Lombardi L, Otsuki T, Maiolo A T, Neri A
出版信息
Leukemia. 2001 May;15(5):864-5. doi: 10.1038/sj.leu.2402097.
PMID:11368454
Abstract
摘要
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Characterization of the t(4;14)(p16.3;q32) in the KMS-18 multiple myeloma cell line.KMS-18多发性骨髓瘤细胞系中t(4;14)(p16.3;q32)的特征分析
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Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3.多发性骨髓瘤中频繁出现的t(4;14)(p16.3;q32.3)易位与成纤维细胞生长因子受体3的表达增加和激活突变相关。
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