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Synthesis of 1-(3-aminopropyl)-4-phenyl-1,2,4-triazolin-5-one and 1-(3-aminopropyl)-3,4-diphenyl-1,2,4-triazolin-5-one.

作者信息

Dobosz M, Maliszewska-Guz A, Struga M, Kleinrok Z, Wielosz-Tokarzewska E, Jagiełło-Wójtowicz E

机构信息

Department of Organic Chemistry, Faculty of Pharmacy, Medical University, 6 Staszica Str., 20-081 Lublin, Poland.

出版信息

Acta Pol Pharm. 2001 Jan-Feb;58(1):35-41.

PMID:11370286
Abstract

The reaction of 4-phenyl-1,2,4-triazolin-5-one [Ia] and 3,4-diphenyl-1,2,4-triazolin-5-one [Ib] with 1-bromo-3-chloropropane was carried out. The obtained compounds [IIa, b] were subjected to the reaction with secondary amines and ethylenediamine with resulted in 1-(3-aminopropyl)-1,2,4-triazolin-5-one derivatives.

摘要

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