Bellantone R, Boscherini M, Lombardi C P, Alesina P F
Divisione di Endocrinochirurgia, Istituto di Clinica Chirurgica, Università Cattolica del S. Cuore, Policlinico A. Gemelli, Roma.
Rays. 2000 Apr-Jun;25(2):267-71.
Medullary thyroid carcinoma is a rare neoplasm (3-9% of all thyroid tumors). Surgery represents the only strategy for potential cure of the disease in whichi. Medullary thyroid carcinoma in which locoregional lymph node metastases are an early occurrence cannot be treated with radioiodine therapy and it is minimally sensitive to chemotherapy and external beam radiation therapy. Therefore total thyroidectomy with lymphadenectomy is the treatment of choice. Ipsilateral laterocervical lymphadenectomy is essential for neoplasms > 10 mm in size in case of central and ipsilateral laterocervical lymph node involvement; bilateral laterocervical lymphadenectomy should be performed in all patients with bilateral lymphadenopathy and in some cases of MEN 2B. In recurrence, reoperation is the single possible treatment with satisfactory results in terms of prognosis.
甲状腺髓样癌是一种罕见的肿瘤（占所有甲状腺肿瘤的3-9%）。手术是该疾病潜在治愈的唯一策略。早期出现局部区域淋巴结转移的甲状腺髓样癌不能用放射性碘治疗，对化疗和外照射放疗敏感性也很低。因此，甲状腺全切除术加淋巴结清扫术是首选治疗方法。对于肿瘤大小>10mm且伴有中央区和同侧颈侧区淋巴结受累的患者，同侧颈侧区淋巴结清扫术至关重要；所有双侧淋巴结病患者以及某些MEN 2B患者均应进行双侧颈侧区淋巴结清扫术。复发时，再次手术是唯一可能的治疗方法，预后结果令人满意。
