Khan S A, de Geus C, Holroyd B, Russell A S
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.
Arch Intern Med. 2001 May 28;161(10):1309-12. doi: 10.1001/archinte.161.10.1309.
Patients presenting with low-trauma wrist fractures are an ideal target population for early case finding of osteoporosis. We decided to investigate whether this early detection occurred in practice.
This study was conducted at a single center in Edmonton, Alberta. A structured interview format was used to contact 112 (72%) of 156 patients older than 40 years who were diagnosed as having an atraumatic fracture of the distal radius/ulna from April 1997 to March 1998 and from January 1999 to February 1999. Information on osteoporosis follow-up and drug therapy was obtained from the patient.
The time between fracture and telephone interview ranged from 6 months to 3 years, with the majority of the sample being interviewed at least 1 year after fracture. Of the 112 patients in this study, 44 had sustained previous fractures, 17 of which had occurred at the wrist, vertebrae, or hip. Sixteen patients in the sample had already sustained a subsequent clinical fracture before our telephone contact. Thirty-two patients had received treatment for osteoporosis before fracture. A further 24 patients (21%) had undergone osteoporosis follow-up after fracture. After fracture, 42 (38%) of all patients were receiving either hormone replacement therapy or using a bisphosphonate.
Only 50% of the study population had received osteoporosis follow-up after fracture. Few patients had any change in their medication use after fracture. The findings in this study population suggest that recognition of the potential for osteoporosis in such patients is inadequate. Given the magnitude of this public health care problem, it is clear that attention to case finding and treatment of osteoporosis should be increased.
低创伤性腕部骨折患者是骨质疏松症早期病例发现的理想目标人群。我们决定调查这种早期检测在实际中是否发生。
本研究在艾伯塔省埃德蒙顿的一个单一中心进行。采用结构化访谈形式联系了1997年4月至1998年3月以及1999年1月至1999年2月期间被诊断为桡骨/尺骨远端无创伤性骨折的156名40岁以上患者中的112名(72%)。从患者处获取了骨质疏松症随访和药物治疗的信息。
骨折与电话访谈之间的时间间隔为6个月至3年,大多数样本在骨折后至少1年接受访谈。在本研究的112名患者中,44名曾有过骨折,其中17名发生在腕部、脊椎或髋部。样本中的16名患者在我们电话联系之前已经发生了后续的临床骨折。32名患者在骨折前接受过骨质疏松症治疗。另有24名患者(21%)在骨折后接受了骨质疏松症随访。骨折后,所有患者中有42名(38%)正在接受激素替代疗法或使用双膦酸盐。
只有50%的研究人群在骨折后接受了骨质疏松症随访。很少有患者在骨折后用药有任何变化。该研究人群的结果表明,对此类患者骨质疏松症可能性的认识不足。鉴于这一公共卫生保健问题的严重性,显然应加强对骨质疏松症病例发现和治疗的关注。