Lottmann H B, Traxer O, Archambaud F, Mercier-Pageyral B
Department of Pediatric Urology, Fondation Hôpital St Joseph, Paris, France.
J Urol. 2001 Jun;165(6 Pt 2):2324-7. doi: 10.1016/S0022-5347(05)66195-2.
We evaluate the efficacy and parenchymal consequences of extracorporeal shock wave lithotripsy (ESWL) for staghorn calculi in children.
From 1991 to 1999, 16 young patients 5.5 months to 2 years old and 7 older children 6 to 11 years old were treated for complete (6) or partial (17) staghorn calculi. Infection was the main factor of lithogenesis, particularly in younger children. In 21 patients the stone burden was more than 20 mm. All patients were treated under general anesthesia using a 14 kV. Sonolith 3000 (14) or a 12 to 20 kV. Nova (9) lithotriptor. In 5 of the 7 older children a Double J section sign stent was inserted before treatment. In the younger children group calculi were fragmented after 1 (11) or 2 (5) sessions. Of the 7 older children 3 required 3 (1) and 4 (2) treatment sessions. To assess the long-term effect of ESWL on the parenchyma, dimercapto-succinic acid renal scan was performed the day before and 6 months after therapy in 20 patients.
Of the 16 younger children 14 became stone-free (87.5%) and 2 had small asymptomatic residual fragments. Of the 7 older children 5 were stone-free (71.4%) and 2 required additional surgery. No steinstrasse or pyelonephritis occurred after ESWL and no parenchymal or ureteral lesion related to ESWL was identified on conventional dimercapto-succinic acid scintigraphy. At a followup of 9 months to 9 years all patients have normal blood pressure.
ESWL as a first option is safe and appropriate for the treatment of staghorn calculi in children particularly in younger children with infected calculi.
我们评估体外冲击波碎石术(ESWL)治疗儿童鹿角形结石的疗效及对实质器官的影响。
1991年至1999年,16例年龄在5.5个月至2岁的幼儿及7例年龄在6至11岁的大龄儿童接受了完全性(6例)或部分性(17例)鹿角形结石的治疗。感染是结石形成的主要因素,尤其在幼儿中。21例患者的结石负荷超过20毫米。所有患者均在全身麻醉下使用14 kV的Sonolith 3000(14例)或12至20 kV的Nova(9例)碎石机进行治疗。7例大龄儿童中有5例在治疗前插入了双J管。幼儿组结石在1次(11例)或2次(5例)治疗后被击碎。7例大龄儿童中有3例需要3次(1例)和4次(2例)治疗。为评估ESWL对实质器官的长期影响,对20例患者在治疗前一天及治疗后6个月进行了二巯基丁二酸肾扫描。
16例幼儿中有14例结石清除(87.5%),2例有小的无症状残留碎片。7例大龄儿童中有5例结石清除(71.4%),2例需要额外手术。ESWL后未发生石街或肾盂肾炎,在传统的二巯基丁二酸闪烁扫描中未发现与ESWL相关的实质器官或输尿管病变。在9个月至9年的随访中,所有患者血压正常。
ESWL作为首选治疗方法,对治疗儿童鹿角形结石是安全且合适的,尤其适用于伴有感染性结石的幼儿。