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[儿童体外冲击波碎石术。通过99m锝二巯丁二酸肾动态显像研究其疗效及评估肾实质损伤:39例儿童系列研究]

[Extracorporeal lithotripsy in children. Study of its efficacy and evaluation of renal parenchymal damage by DMSA-Tc 99m scintigraphy: a series of 39 children].

作者信息

Traxer O, Lottmann H, Archambaud F, Helal B, Mercier-Pageyral B

机构信息

Service de chirurgie urologique pédiatrique, fondation hôpital Saint-Joseph, Paris, France.

出版信息

Arch Pediatr. 1999 Mar;6(3):251-8. doi: 10.1016/s0929-693x(99)80260-7.

Abstract

AIM

The objectives of the study were to confirm the efficacy of extracorporeal shock wave lithotripsy (ESWL) in infants and children and to evaluate potential long-term renal parenchymal damage by 99m Tc DMSA renal scan.

MATERIALS AND METHODS

Between November 1989 and November 1997, 39 children between 10 months and 17-1/2 years of age (average: 7 years) were treated by extracorporeal shock wave lithotripsy for kidney or ureteral stones with a Sonolith 3000 lithotriptor (Technomed Corp). Forty-six stones were treated. Eight metabolic and 11 urological abnormalities were identified. The evaluation of the treatment and its consequences were based on a clinical examination, conventional imaging and a DMSA renal scan performed 24 h before extracorporeal shock wave lithotripsy and at least 6 months after treatment.

RESULTS

Treatment was successful (stone fragmented and eliminated) in 84.6% at 3 months after one to four sessions. Sixty-one sessions were necessary and two patients underwent open surgery for failed extracorporeal shock wave lithotripsy. Three recurrences were also retreated. At long term follow-up (6 months to 8 years) no incidents of high blood pressure were observed, nor parenchymal lesions imputable to extracorporeal shock wave lithotripsy.

CONCLUSIONS

The efficacy of the extracorporeal shock wave lithotripsy for children is proven. This study also confirms the innocuousness of extracorporeal shock wave lithotripsy for renal parenchyma even in infants. However, long term follow-up and further evaluation with the other categories of lithotriptors are necessary to make definitive conclusions.

摘要

目的

本研究的目的是证实体外冲击波碎石术(ESWL)在婴幼儿及儿童中的疗效,并通过99m锝二巯丁二酸(99mTc DMSA)肾扫描评估潜在的长期肾实质损害。

材料与方法

1989年11月至1997年11月期间,使用Sonolith 3000碎石机(Technomed公司)对39例年龄在10个月至17.5岁(平均7岁)的儿童进行体外冲击波碎石术治疗肾或输尿管结石。共治疗46颗结石。发现8例代谢异常和11例泌尿系统异常。治疗及其后果的评估基于临床检查、传统影像学检查以及在体外冲击波碎石术前24小时和治疗后至少6个月进行的DMSA肾扫描。

结果

一至四次治疗后3个月时,治疗成功率为84.6%。共进行了61次治疗,2例患者因体外冲击波碎石术失败接受了开放手术。3例复发患者也接受了再次治疗。在长期随访(6个月至8年)中,未观察到高血压事件,也未发现可归因于体外冲击波碎石术的实质病变。

结论

体外冲击波碎石术对儿童的疗效得到证实。本研究还证实了体外冲击波碎石术即使对婴儿的肾实质也是无害的。然而,需要长期随访并使用其他类型的碎石机进行进一步评估才能得出明确结论。

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