Wilson S E, Hiatt J, Winston M, Passaro E
Arch Surg. 1975 Jul;110(7):797-801. doi: 10.1001/archsurg.1975.01360130029006.
Clearance of a parenchymal injection of xenon Xe 133 from the jejunum was used to asses changes in tissue perfusion produced by variations in superiorr mesenteric artery flow resulting from partial aortic occlusion. Disappearance of xenon from submucosa and muscularis was similar and reproducible. The biexponential function of the isotope clearanc exhibited a rapid initial component representing mean flow. Calculated xenon clearance rates, expressed as half-times for isotope disappearance and plotted as a function of decreasing superior mesenteric artery flow, were characteristically rapid for a broad range of superio mesenteric artery flows (90 to 600 ml/min). With reduction of superior mesenteric artery flow beyond 80 plus or minus 10 ml/min, tissue clearance of xenon was markedly prolonged. Adequate perfusion of the vascular compartments of the small bowel as measured by xenon clearance was maintained until 80% reduction of superior mesenteric artery flow.
通过检测空肠实质注射的氙Xe 133的清除情况，来评估部分主动脉闭塞导致肠系膜上动脉血流变化所引起的组织灌注变化。氙在黏膜下层和肌层的消失情况相似且可重复。同位素清除的双指数函数呈现出一个快速的初始成分，代表平均血流。计算得到的氙清除率，以同位素消失的半衰期表示，并绘制为肠系膜上动脉血流减少的函数，在广泛的肠系膜上动脉血流范围（90至600毫升/分钟）内，其特征是清除速度很快。当肠系膜上动脉血流减少超过80±10毫升/分钟时，氙的组织清除明显延长。通过氙清除测量，在肠系膜上动脉血流减少80%之前，小肠血管腔的灌注仍保持充足。
