Cho K W, Lee H S, Rho J R, Kim T S, Mo S J, Shin J
Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan P.O. Box 29, Seoul 425-600, Korea.
J Nat Prod. 2001 May;64(5):664-7. doi: 10.1021/np000599g.
Six novel metabolites containing a lactone moiety as a common structural feature, along with the previously described (-)-blastmycinolactol, have been isolated from the cultivation broth of a bacterium of the genus Streptomyces isolated from marine sediment. On the basis of the results of combined spectroscopic analysis, the structures of the new compounds have been determined as butenolides and 3-hydroxy-gamma-butyrolactones.
从海洋沉积物中分离出的链霉菌属细菌的培养液中,已分离出六种具有内酯部分作为共同结构特征的新型代谢物,以及先前描述的(-)-杀稻瘟菌素内酯醇。基于联合光谱分析的结果,新化合物的结构已确定为丁烯内酯和3-羟基-γ-丁内酯。