Goluszko P, Selvarangan R, Nowicki B J, Nowicki S, Hart A, Pawelczyk E, Nguyen K
Department of Obstetrics & Gynecology, The University of Texas Medical Branch, Galveston, TX 77555-1062, USA.
J Clin Microbiol. 2001 Jun;39(6):2317-20. doi: 10.1128/JCM.39.6.2317-2320.2001.
Infections caused by Escherichia coli isolates expressing adhesins of the Dr family are associated with diarrhea and urinary tract infections, and these E. coli strains recognize the complement regulatory protein decay-accelerating factor (DAF) as their receptor. Clustering of the DAF receptor at the sites of bacterial adherence to epithelial cells is proposed as an alternative to PCR assay for rapid detection of Dr-positive E. coli.
表达Dr家族黏附素的大肠杆菌分离株引起的感染与腹泻和尿路感染有关,并且这些大肠杆菌菌株将补体调节蛋白衰变加速因子(DAF)识别为它们的受体。DAF受体在细菌黏附上皮细胞部位的聚集被提议作为一种替代PCR检测法,用于快速检测Dr阳性大肠杆菌。