Kang T C, Lee J C, Choi K Y, Park S K, Jeong Y G, Jo S M, Won M H
Department of Anatomy, College of Medicine, Hallym University, Chunchon 200-702, South Korea.
Anat Histol Embryol. 2001 Apr;30(2):117-20.
The distribution of serotonin immunoreactivity in the main olfactory bulb (MOB) of the Mongolian gerbil (Meriones unguiculatus) was examined by immunohistochemistry. Seven distinct layers of the Mongolian gerbil MOB-stained with cresyl violet were identified. Serotonin-immunoreactive (IR) cell bodies were not found in the MOB. The serotonin-IR nerve fibres had a specific laminar distribution and morphology in the gerbil MOB. Serotonin-IR nerve fibres were observed in the glomerular, external plexiform and granule cell layers of the MOB. These serotonin-IR nerve fibres showed varicosities that were larger than the thickness of the axon. The highest density of serotonin-IR nerve fibres was in glomeruli of the glomerular layer. The average fibre density in the glomerular layer was more than three to four times the density in the infraglomerular layers. Glomerular serotonin-IR fibres were much more intensively stained than infraglomerular serotonin-IR fibres. This result suggests that serotonin-IR nerve fibres of Mongolian gerbil MOB are extrinsic and may act to modulate the olfactory transmission.
通过免疫组织化学方法研究了蒙古沙鼠（Meriones unguiculatus）主嗅球（MOB）中5-羟色胺免疫反应性的分布。用甲酚紫染色鉴定了蒙古沙鼠MOB的七个不同层。在MOB中未发现5-羟色胺免疫反应性（IR）细胞体。5-羟色胺-IR神经纤维在沙鼠MOB中具有特定的层状分布和形态。在MOB的肾小球层、外丛状层和颗粒细胞层中观察到5-羟色胺-IR神经纤维。这些5-羟色胺-IR神经纤维显示出比轴突厚度更大的膨体。5-羟色胺-IR神经纤维的最高密度位于肾小球层的肾小球中。肾小球层的平均纤维密度是肾小球下层密度的三到四倍以上。肾小球5-羟色胺-IR纤维的染色比肾小球下5-羟色胺-IR纤维强烈得多。这一结果表明，蒙古沙鼠MOB的5-羟色胺-IR神经纤维是外在的，可能起到调节嗅觉传递的作用。
