Miles K L, Norwich J T, Martinson J J, Clegg J B
MRC Molecular Haematology Unit, Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
Br J Haematol. 2001 Jun;113(3):694-8. doi: 10.1046/j.1365-2141.2001.02823.x.
Polymerase chain reaction protocols were designed specifically to amplify regions of the alpha globin complex that contain the nine common polymorphic haplotyping sites. These reactions provided a quicker and more sensitive approach to determining alpha globin haplotypes than Southern blotting methods.
聚合酶链反应方案专门设计用于扩增α珠蛋白复合体中包含九个常见多态性单倍型位点的区域。与Southern印迹法相比，这些反应为确定α珠蛋白单倍型提供了一种更快、更灵敏的方法。
