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以脊髓髓内病变形式出现的结节病。

Sarcoidosis presenting as an intramedullary spinal cord lesion.

作者信息

Maroun F B, O'Dea F J, Mathieson G, Fox G, Murray G, Jacob J C, Reddy R, Avery R

机构信息

Department of Radiology, Memorial University of Newfoundland, Health Sciences Centre, St John's, Canada.

出版信息

Can J Neurol Sci. 2001 May;28(2):163-6. doi: 10.1017/s0317167100052884.

Abstract

OBJECTIVES

Sarcoidosis affects the spinal cord in only 0.43% of patients with sarcoidosis. Usually there is systemic involvement prior to the development of cord lesions. We present a case of sarcoid isolated to the intramedullary spinal cord, which was a diagnostic and therapeutic challenge. We review the case and then present a review of the literature with an emphasis on presentation, diagnosis and treatment.

METHODS

We have reviewed a patient who presented with an isolated sarcoid granuloma affecting the cervical spinal cord. All pertinent history and physical information was extracted from the patient's chart and through patient interview. Laboratory, radiographic and pathological investigations are presented.

RESULTS AND CONCLUSIONS

Fourteen patients have been reported with isolated intramedullary spinal cord sarcoidosis. Current practice supports the role of surgery for biopsy; mainstay of treatment is corticosteroids.

摘要

目的

结节病仅在0.43%的结节病患者中累及脊髓。通常在脊髓病变出现之前已有全身受累。我们报告一例孤立于脊髓髓内的结节病病例,这是一个诊断和治疗上的挑战。我们回顾该病例,并对文献进行综述,重点关注临床表现、诊断和治疗。

方法

我们回顾了一名出现孤立性结节病肉芽肿累及颈髓的患者。所有相关病史和体格检查信息均从患者病历及通过患者访谈获取。展示了实验室、影像学和病理学检查结果。

结果与结论

已报道14例孤立性脊髓髓内结节病患者。目前的做法支持手术活检的作用;治疗的主要手段是皮质类固醇。

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