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健康年轻女性疑似髓内脊髓结节病。

Presumed intramedullary spinal cord sarcoidosis in a healthy young adult woman.

机构信息

Department of Physical Medicine and Rehabilitation, University of Virginia, Charlottesville, VA 22908-1004, USA.

出版信息

Am J Phys Med Rehabil. 2012 Sep;91(9):810-3. doi: 10.1097/PHM.0b013e31824121a8.

Abstract

Sarcoidosis is an inflammatory disease of unknown etiology associated with the development of granulomatous nodules in various organs, most commonly the lungs, eyes, and skin. It rarely affects the central nervous system, with the spinal cord being least common area of involvement. However, when sarcoidosis does affect the central nervous system, it is often the first presentation of the disease, making diagnosis more difficult. Physical examination findings are consistent with spinal cord pathology, and imaging often suggests spinal cord tumor. We present a case of an otherwise healthy young woman with a granulomatous mass in her cervico-thoracic spinal cord presumed to be sarcoid and review the clinical findings, diagnosis, treatment, and prognosis associated with this rare disease.

摘要

结节病是一种病因不明的炎症性疾病,可导致肺部、眼睛和皮肤等多种器官出现肉芽肿性结节。它很少影响中枢神经系统,而脊髓是最不常见的受累部位。然而,当结节病确实影响中枢神经系统时,它通常是该疾病的首发表现,从而使诊断更加困难。体格检查结果与脊髓病理一致,影像学检查常提示脊髓肿瘤。我们报告了一例健康年轻女性,其颈胸段脊髓存在肉芽肿性肿块,推测为结节病,并回顾了与这种罕见疾病相关的临床发现、诊断、治疗和预后。

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