Carattoli A, Villa L, Pezzella C, Bordi E, Visca P
Istituto Superiore di Sanità, Rome, Italy.
Emerg Infect Dis. 2001 May-Jun;7(3):444-7. doi: 10.3201/eid0703.010314.
We conducted a 30-year retrospective analysis of IncFI plasmids from Salmonella enterica serotype Typhimurium. These plasmids have been associated with the emergence of epidemic clones of multidrug-resistant Salmonella. Molecular and genetic evidence indicates that IncFI plasmids are evolving through sequential acquisition of integrons carrying different arrays of antibiotic- resistance genes.