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Inhibition of histaminase release from human granulocytes by products of histaminase activity.

作者信息

Herman J J, Brenner J K, Colten H R

出版信息

Science. 1979 Oct 5;206(4414):77-8. doi: 10.1126/science.113872.

DOI:10.1126/science.113872
PMID:113872
Abstract

Imidazoleacetic acid, a product of the action of histaminase (E.C. 1.4.3.6) on histamine, inhibits specific release of histaminase from human peripheral blood granulocytes with an inhibition constant between 5 X 10(-9)M and 1 X 10(-8)M. Hence, modulation of enzyme release is indirectly mediated by the activity of the enzyme.

摘要

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