脊椎动物光感受器中信号产生的机制。

Mechanisms of generation of signals in vertebrate photoreceptors.

作者信息

Cervetto L, Torre V, Capovilla M

出版信息

Sens Processes. 1978 Dec;2(4):316-20.

Abstract

The electrical responses of rods are analyzed in different ionic environments. It is shown that the dark level of the membrane potential is predominantly determined by a sodium current, while the peak of responses to bright light is controlled by the concentration of external potassium. The sag from the peak to the plateau of photoresponses seems to be generated by different ionic mechanism. The effects produced by substituting the external calcium with EGTA are also analyzed. It is suggested that calcium plays a role in different mechanisms of generation of electrical responses.

摘要

在不同离子环境中分析了视杆细胞的电反应。结果表明，膜电位的暗水平主要由钠电流决定，而对强光反应的峰值则由细胞外钾离子浓度控制。光反应从峰值到平台期的下降似乎是由不同的离子机制产生的。还分析了用乙二醇双四乙酸（EGTA）替代细胞外钙所产生的影响。研究表明，钙在电反应产生的不同机制中发挥作用。