Grady D M, McHardy F, Wong J, Jin F, Tong D, Chung F
Department of Anesthesia, Toronto Western Hospital, University of Toronto, Ontario, Canada.
Anesthesiology. 2001 May;94(5):760-6. doi: 10.1097/00000542-200105000-00012.
Currently, the manufacturer of the laryngeal mask airway (LMA; Laryngeal Mask Company, Ltd., Northfield End, Henley on Thames, Oxon, United Kingdom) recommends using as large a mask size as possible. The aim of this study was to compare the incidence of pharyngolaryngeal morbidity after the use of a large (size 5 in males and size 4 in females) or small (size 4 in males and size 3 in females) LMA in spontaneously breathing patients.
A total of 258 male and female patients were randomly assigned to insertion of a large or small LMA while breathing spontaneously during general anesthesia. After insertion of the LMA, a "just-seal" cuff pressure was obtained, and intracuff pressure was measured at 10-min intervals until just before removal of the LMA. The 2- and 24-h incidence of postoperative sore throat, pain, hoarseness, dysphagia, and nausea and vomiting was assessed. Complications after LMA removal, including body movement, coughing, retching, regurgitation, vomiting, biting on the LMA, bronchospasm, laryngospasm, or the presence of blood on the LMA, were recorded.
The use of a large LMA was associated with a higher incidence of sore throat in both sexes (20% vs. 7% in men, 21% vs. 5% in women; P < 0.05) and a higher incidence of hoarseness in male patients at 2 h postoperatively (21% vs. 9%, P < 0.05). There was a higher incidence of sore throat in male patients at 24 h postoperatively with the use of a large LMA (26% vs. 12%, P < 0.05). There was no difference in the incidence of complications of LMA removal orother pharyngolaryngeal morbidity, such as difficulty swallowing, drinking, and eating, or nausea and vomiting, between male or female groups at any time period with the use of a large LMA.
Selection of a small laryngeal mask airway (size 4) in spontaneously breathing male patients may be more appropriate to limit the occurrence of sore throat on the first postoperative day. All patients had a fourfold increased risk of developing sore throat when a large LMA was used.
目前,喉罩气道(LMA;喉罩公司,英国牛津郡泰晤士河畔亨利镇诺斯菲尔德恩德)的制造商建议尽可能使用大尺寸的面罩。本研究的目的是比较在自主呼吸患者中使用大尺寸(男性用5号,女性用4号)或小尺寸(男性用4号,女性用3号)LMA后咽喉部发病率。
总共258例男性和女性患者在全身麻醉期间自主呼吸时被随机分配插入大尺寸或小尺寸的LMA。插入LMA后,获得“刚好密封”的套囊压力,并每隔10分钟测量套囊内压力,直到即将移除LMA之前。评估术后2小时和24小时咽痛、疼痛、声音嘶哑、吞咽困难以及恶心和呕吐的发生率。记录移除LMA后的并发症,包括身体移动、咳嗽、干呕、反流、呕吐、咬LMA、支气管痉挛、喉痉挛或LMA上有血迹。
使用大尺寸LMA在两性中均与较高的咽痛发生率相关(男性中为20% 对7%,女性中为21% 对5%;P < 0.05),并且在术后2小时男性患者中声音嘶哑的发生率较高(21% 对9%,P < 0.05)。使用大尺寸LMA时,男性患者术后24小时咽痛的发生率较高(26% 对12%,P < 0.05)。在任何时间段,使用大尺寸LMA时,男性或女性组在LMA移除并发症或其他咽喉部发病率方面,如吞咽、饮水和进食困难,或恶心和呕吐方面没有差异。
对于自主呼吸的男性患者,选择小尺寸喉罩气道(4号)可能更适合限制术后第一天咽痛的发生。当使用大尺寸LMA时,所有患者发生咽痛的风险增加四倍。