Rahbar S, Mahdavi N, Nowzari G, Mostafavi I
Biochim Biophys Acta. 1975 Apr 29;386(2):525-9. doi: 10.1016/0005-2795(75)90295-0.
A new haemoglobin variant (haemoglobin Arya), is described from an Iranian female. The substitution is at residue 47 (CD5) of the alpha chain in which aspartic acid has been substituted by asparagine. The presence of haemoglobin Arya was not associated with clinical symptoms. This variant has normal stability at 50 degrees C, but is slightly unstable when tested at 55 degrees C.
从一名伊朗女性身上发现了一种新的血红蛋白变体(血红蛋白阿亚)。该变体位于α链的第47位残基(CD5),天冬氨酸被天冬酰胺取代。血红蛋白阿亚的存在与临床症状无关。这种变体在50摄氏度时稳定性正常,但在55摄氏度测试时略显不稳定。