Geschwind D H
Department of Neurology, University of California, Los Angeles, School of Medicine, 710 Westwood Plaza, Los Angeles, California 90095-1769, USA.
Nat Rev Neurosci. 2001 Jun;2(6):435-8. doi: 10.1038/35077576.
Sharing of microarray data has many advantages for the scientific and biomedical community, and should be advocated by neuroscience journals. The goals of sharing are manifold, and include improving analysis and confidence in results, and facilitating global comparisons between experiments, while at the same time, not penalizing those who share. The sharing of microarray data poses unique challenges relative to more generic data such as DNA sequences. These challenges are surmountable, and various sharing formats are possible. Centralized non-commercial databases are being developed to facilitate this process.
微阵列数据的共享对科学界和生物医学界具有诸多益处,神经科学期刊应予以倡导。共享的目标是多方面的,包括改进分析方法、增强对结果的信心、促进不同实验之间的全球比较,同时,不对数据共享者进行惩罚。与诸如DNA序列等更一般的数据相比,微阵列数据的共享带来了独特的挑战。这些挑战是可以克服的,并且存在多种共享格式。正在开发集中式非商业数据库以推动这一进程。