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[抗高血压药物治疗:不良反应与药物相互作用]

[Antihypertensive drug therapy: adverse effects and drug interactions].

作者信息

Takishita S

机构信息

Third Department of Internal Medicine, University of Ryukyus School of Medicine.

出版信息

Nihon Rinsho. 2001 May;59(5):992-7.

Abstract

The number of classes of antihypertensive drugs has been growing. The options of choice of the drugs now are so great that it seems not to be difficult to reduce blood pressure effectively. Newly developed classes have been shown to provide beneficial effects in variety of hypertension-related processes. However, each drug shows significant differences in adverse effects, incidental properties and interactions with non-antihypertensive drugs. To improve quality of life, compliance with medication, and beneficial effects on pathophysiological and cardiovascular risk conditions of patients, we should be well acquainted with adverse effects and possible disadvantages produced by antihypertensive drugs in particular situations.

摘要

抗高血压药物的种类一直在增加。如今药物的选择如此之多,以至于有效降低血压似乎并不困难。新开发的药物类别已被证明在各种与高血压相关的过程中都有有益作用。然而,每种药物在不良反应、附带特性以及与非抗高血压药物的相互作用方面都存在显著差异。为了提高患者的生活质量、用药依从性以及对病理生理和心血管风险状况的有益影响,我们应该充分了解抗高血压药物在特定情况下产生的不良反应和可能的弊端。

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