Bassukas I D, Hofmockel G
Department of Dermatology, Medical University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany.
Anticancer Res. 2001 Mar-Apr;21(2A):1181-2.
Tumour growth curve experiments play an important role in experimental oncology and established methods exist for their unbiased interpretation. However, many authors till introduce systemic biases to their data by using the so-called "relative tumour size" transformation, inspite of wide awarance about the limitations of this latter method. With this communication and by using a fictive exaggeration of the problems connected with the application of this transformation we would like to appeal to both authors and reviewers likewise to ban this potential source of misinterpretation from the oncological literature.
肿瘤生长曲线实验在实验肿瘤学中发挥着重要作用，并且存在对其进行无偏解释的既定方法。然而，尽管许多人都清楚后一种方法的局限性，但仍有许多作者通过使用所谓的“相对肿瘤大小”转换，将系统性偏差引入到他们的数据中。通过本通讯以及对与这种转换应用相关问题进行虚拟的夸张，我们希望同样呼吁作者和审稿人，从肿瘤学文献中杜绝这种潜在的误解来源。
