Palmer R J, Wu R, Gordon S, Bloomquist C G, Liljemark W F, Kilian M, Kolenbrander P E
National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Methods Enzymol. 2001;337:393-403. doi: 10.1016/s0076-6879(01)37028-3.
With the use of the removable stents or bonded enamel piece models with or without a continuous bacterial layer, many in vitro or in vivo studies can be initiated. For example, studies on salivary pellicle formation, surface characteristics of biomaterials as they affect plaque development, antiplaque agents, the dynamics of adhesion of bacteria, interspecies adhesion of bacteria, the colonization of bacteria, the dynamics of bacterial growth in vivo, and the succession of growth in older supragingival plaques can be carried out.
使用带有或不带有连续细菌层的可移除支架或粘结牙釉质片模型,可以开展许多体外或体内研究。例如,可以进行关于唾液薄膜形成、生物材料表面特性对菌斑形成的影响、抗菌斑剂、细菌黏附动力学、细菌种间黏附、细菌定植、体内细菌生长动力学以及老年龈上菌斑生长演替等方面的研究。