Due-Tønnessen B, Helseth E, Skullerud K, Lundar T
Department of Neurosurgery, The National Hospital, Oslo, Norway.
Childs Nerv Syst. 2001 Apr;17(4-5):252-6. doi: 10.1007/pl00013728.
Choroid plexus tumors are rare intraventricular tumors, and they represent 2-4% of brain tumors in children. This single-institution retrospective study involves 16 consecutive choroid plexus tumors: 13 papillomas and 3 carcinomas. Tumor locations were the lateral ventricles in 13 cases, the third ventricle in 2 cases and the fourth ventricle in 1 case. The mean age at presentation was 3.1 years. Two patients died of perioperative blood loss. Five-year survival was 85% with papillomas and 33% with carcinomas. None of the papillomas recurred after total tumor resection, and the functional outcome in long-term survivors after papilloma surgery was excellent in 92% of the cases. Two of the carcinoma patients had disseminated disease. Fifty percent of the patients had persistent hydrocephalus after tumor resection, and these required cerebrospinal fluid diversion.
脉络丛肿瘤是罕见的脑室内肿瘤,占儿童脑肿瘤的2% - 4%。这项单机构回顾性研究纳入了16例连续的脉络丛肿瘤病例:13例乳头状瘤和3例癌。肿瘤位置:13例位于侧脑室,2例位于第三脑室,1例位于第四脑室。发病时的平均年龄为3.1岁。两名患者死于围手术期失血。乳头状瘤的5年生存率为85%,癌的5年生存率为33%。全肿瘤切除后,乳头状瘤无一复发,乳头状瘤手术后长期存活者中92%的功能预后良好。两名癌患者出现了播散性疾病。50%的患者在肿瘤切除后仍有持续性脑积水,这些患者需要进行脑脊液分流。