红霉素与土霉素治疗绵羊腐蹄病的比较

Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot.

作者信息

Píriz S, Pobel T, Jiménez R, Mateos E M, Martín-Palomino P, Vila P, Vadillo S

机构信息

Unit of Microbiology, Department of Medicine and Animal Health, Veterinary Faculty, University of Extremadura, 10071 Cáceres, Spain.

出版信息

Acta Vet Hung. 2001;49(2):131-9. doi: 10.1556/004.49.2001.2.2.

DOI:10.1556/004.49.2001.2.2

PMID:11402641

Abstract

A microbiological study of 25 cases of ovine footrot was performed. Cultures belonging to Dichelobacter nodosus were isolated in 48% of the sampled animals. The sensitivity of the 99 strict anaerobic bacterial isolates to 5 antibiotics (penicillin G, amoxycillin, spiramycin, erythromycin and oxytetracycline) was studied. The percentage of resistant cultures was in all cases higher than 30%. The efficacy of erythromycin and oxytetracycline in the treatment of ovine footrot was studied. To conduct this test, an intramuscular injection was applied, of one antimicrobial or the other, at the beginning of the treatment. The tolerance of animals to the antimicrobials, the success rate of treatment and the severity of lameness were evaluated. The percentage of animals cured within 15 days was around 75%. In contrast, only 44% improvement was achieved in the lameness. No differences were found between the two antimicrobials in the above indices.

摘要

对25例羊腐蹄病进行了微生物学研究。在48%的采样动物中分离出了结节拟杆菌培养物。研究了99株严格厌氧菌分离株对5种抗生素（青霉素G、阿莫西林、螺旋霉素、红霉素和土霉素）的敏感性。在所有情况下，耐药培养物的百分比均高于30%。研究了红霉素和土霉素治疗羊腐蹄病的疗效。为进行该试验，在治疗开始时对动物进行肌肉注射，注射其中一种抗菌药物。评估了动物对抗菌药物的耐受性、治疗成功率和跛行严重程度。15天内治愈的动物百分比约为75%。相比之下，跛行改善率仅为44%。在上述指标方面，两种抗菌药物之间未发现差异。