Allen A L, Siegfried E C
Department of Dermatology, Saint Louis University Medical Center, Missouri 63104, USA.
Adolesc Med. 2001 Jun;12(2):vi, 229-42.
Warts continue to be a therapeutic challenge, especially when they are numerous or widespread; in contrast, treatment of molluscum is comparatively more successful. A single, most effective treatment for either infection has not been defined. Conventional methods attempt to non-specifically destroy infected tissue. Most of these procedures are painful and require multiple treatments or compliance with daily application of a medication. The efficacy of destructive techniques has not been verified in placebo-controlled clinical trials and success rates reported in uncontrolled studies are difficult to interpret and often no better than that those achieved with a placebo. Alternative pharmacological approaches are aimed at stimulating immunologic or antiviral responses. Further study is needed to establish efficacy of these treatments.
疣仍然是一个治疗难题，尤其是当它们数量众多或广泛分布时；相比之下，传染性软疣的治疗相对更成功。尚未确定针对这两种感染的单一最有效治疗方法。传统方法试图非特异性地破坏受感染组织。这些方法大多很痛苦，需要多次治疗或坚持每日用药。破坏性技术的疗效尚未在安慰剂对照临床试验中得到验证，非对照研究报告的成功率难以解释，而且往往并不比安慰剂治疗的效果更好。替代药理学方法旨在刺激免疫或抗病毒反应。需要进一步研究来确定这些治疗方法的疗效。
