Li K K, Troell R J, Riley R W, Powell N B, Koester U, Guilleminault C
Stanford University Sleep Disorders and Research Center, Stanford, California, USA.
Laryngoscope. 2001 Jun;111(6):1075-8. doi: 10.1097/00005537-200106000-00027.
To evaluate the presence of velopharyngeal insufficiency (VPI) symptoms and the associated changes of the velopharyngeal anatomy in patients who underwent maxillomandibular advancement (MMA) for persistent obstructive sleep apnea (OSA) after uvulopalatopharyngoplasty (UPPP).
Preoperative and postoperative cephalometric radiographs were analyzed to assess the anatomic changes of the velopharynx. In addition, a questionnaire survey was sent to the patients between 6 to 12 months after MMA. The questionnaires evaluated the presence and extent of VPI symptoms, including nasal regurgitation while eating or drinking as well as hypernasal speech. A 10-cm visual analog scale (VAS 0-10) was included to assess the impact of VPI symptoms on the patient's quality of life. In the patients who reported VPI symptoms, telephone interviews were conducted 1 year after the survey to evaluate the changes in VPI symptoms over time.
Fifty-two of the 65 questionnaires were returned. Five patients (9.6%) reported nasal regurgitation of liquids when drinking hastily, with 2 patients reporting the occurrences as occasional and 3 patients reporting as rare. The impact of these symptoms on the patient's quality of life was minimal (VAS 0.6 +/- 0.4). Regurgitation of food or hypernasal speech was not reported. The telephone interviews 1 year later revealed that the symptoms have completely resolved in all 5 patients. Comparison of the preoperative and postoperative cephalometric radiographs demonstrated the pharyngeal depth increase was 48% of the amount of maxillary advancement and the functional pharyngeal length increased 53% of the maxillary advancement. The functional depth of the pharynx after MMA was significantly greater in the patients with VPI symptoms (P=.01).
The results of this study suggest that patients who undergo MMA for persistent OSA after UPPP have a low risk of developing VPI. If symptoms occur postoperatively, they are mild and have minimal effect on the patient's quality of life; moreover, the symptoms usually resolve over time.
评估在接受悬雍垂腭咽成形术(UPPP)后因持续性阻塞性睡眠呼吸暂停(OSA)而接受上颌下颌前移术(MMA)的患者中腭咽闭合不全(VPI)症状的存在情况以及腭咽解剖结构的相关变化。
分析术前和术后的头影测量X线片以评估腭咽的解剖变化。此外,在MMA术后6至12个月向患者发送问卷调查。问卷评估了VPI症状的存在和程度,包括进食或饮水时的鼻反流以及鼻音过重。纳入一个10厘米的视觉模拟量表(VAS 0 - 10)以评估VPI症状对患者生活质量的影响。在报告有VPI症状的患者中,在调查后1年进行电话访谈以评估VPI症状随时间的变化。
65份问卷中有52份被退回。5名患者(9.6%)报告在匆忙饮水时有液体鼻反流,其中2名患者报告这种情况为偶尔发生,3名患者报告为罕见。这些症状对患者生活质量的影响极小(VAS 0.6±0.4)。未报告食物反流或鼻音过重。1年后的电话访谈显示所有5名患者的症状已完全缓解。术前和术后头影测量X线片的比较表明,咽深度增加量为上颌前移量的48%,功能性咽长度增加量为上颌前移量的53%。有VPI症状的患者在MMA术后咽的功能深度明显更大(P = 0.01)。
本研究结果表明,UPPP后因持续性OSA接受MMA的患者发生VPI的风险较低。如果术后出现症状,症状较轻且对患者生活质量影响极小;此外,症状通常会随时间缓解。