促红细胞生成素的肾脏抑制剂
[Renal inhibitor of erythropoietin].
作者信息
Moiseeva O I
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1975 May;61(5):744-8.
PMID:1140465
Abstract
The soluble fraction of the rat and rabbit renal homogenate (normal, after acute blood loss or cobalt chlorate administration) contains an erythropoietin inhibitor and interferes with transformation of the renal erythropoiesis--stimulating factor into erythropoietin. After subcutaneous administration of this fraction in intact rats, an erythropoiesis inhibitor was revealed in their plasma.
摘要
大鼠和家兔肾脏匀浆的可溶部分（正常、急性失血后或给予氯酸钴后）含有促红细胞生成素抑制剂，并干扰肾脏促红细胞生成刺激因子向促红细胞生成素的转化。在完整大鼠皮下注射该部分后，在其血浆中发现了促红细胞生成抑制因子。
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