Lucroy M D, Peck J N, Berry C R
Affiliated Veterinary Specialists, Winter Park, FL 32789, USA.
Vet Radiol Ultrasound. 2001 May-Jun;42(3):218-20. doi: 10.1111/j.1740-8261.2001.tb00927.x.
A 6-year-old neutered male Rottweiler was examined for a progressive right pelvic limb lameness. In radiographs of the right stifle, there was an osteolytic lesion with irregular new bone formation along the cranial aspect of the patella consistent with an aggressive bone lesion. In thoracic radiographs, there were multiple soft tissue nodular opacities throughout the lung fields, consistent with pulmonary metastases. Microscopically, fine needle aspirate samples from the right patella contained pleomorphic spindle cells with cytologic features of osteosarcoma. The presence of pulmonary metastases at the time of initial diagnosis in the dog described herein suggests that osteosarcoma of the patella has the potential for similar aggressive biologic behavior as that seen in dogs with appendicular osteosarcoma.
一只6岁已绝育的雄性罗威纳犬因右后肢渐进性跛行接受检查。在右膝关节的X光片中，髌骨前方有一个溶骨性病变，并伴有不规则的新骨形成，符合侵袭性骨病变。在胸部X光片中，整个肺野有多个软组织结节状阴影，符合肺转移。显微镜下，右髌骨的细针穿刺样本中含有多形性梭形细胞，具有骨肉瘤的细胞学特征。本文所述犬在初次诊断时即存在肺转移，提示髌骨骨肉瘤可能具有与四肢骨肉瘤相似的侵袭性生物学行为。
