Kwan I, Bunn F, Roberts I
Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London, UK, WC1N 1EH.
Cochrane Database Syst Rev. 2001;2001(2):CD002803. doi: 10.1002/14651858.CD002803.
Spinal immobilisation involves the use of a number of devices and strategies to stabilise the spinal column after injury and thus prevent spinal cord damage. The practice is widely recommended and widely used in trauma patients with suspected spinal cord injury in the pre-hospital setting.
To quantify the effect of different methods of spinal immobilisation (including immobilisation versus no immobilisation) on mortality, neurological disability, spinal stability and adverse effects in trauma patients.
We searched the Cochrane Controlled Trial Register (CCTR), the specialised register of the Cochrane Injuries Group, MEDLINE, EMBASE, CINAHL, PubMed and the National Research Register. We checked reference lists of all articles and contacted experts in the field to identify eligible trials. Manufacturers of spinal immobilisation devices were also contacted for information.
Randomised controlled trials comparing spinal immobilisation strategies in trauma patients with suspected spinal cord injury. Trials in healthy volunteers were excluded.
Two reviewers independently applied eligibility criteria to trial reports and extracted data.
We found no randomised controlled trials of spinal immobilisation strategies in trauma patients.
REVIEWER'S CONCLUSIONS: We did not find any randomised controlled trials that met the inclusion criteria. The effect of spinal immobilisation on mortality, neurological injury, spinal stability and adverse effects in trauma patients remains uncertain. Because airway obstruction is a major cause of preventable death in trauma patients, and spinal immobilisation, particularly of the cervical spine, can contribute to airway compromise, the possibility that immobilisation may increase mortality and morbidity cannot be excluded. Large prospective studies are needed to validate the decision criteria for spinal immobilisation in trauma patients with high risk of spinal injury. Randomised controlled trials in trauma patients are required to establish the relative effectiveness of alternative strategies for spinal immobilisation.
脊柱固定术涉及使用多种设备和策略,在损伤后稳定脊柱,从而预防脊髓损伤。在院前环境中,该做法被广泛推荐并广泛应用于疑似脊髓损伤的创伤患者。
量化不同脊柱固定方法(包括固定与不固定)对创伤患者死亡率、神经功能障碍、脊柱稳定性及不良反应的影响。
我们检索了Cochrane对照试验注册库(CCTR)、Cochrane损伤组专业注册库、医学索引数据库(MEDLINE)、荷兰医学文摘数据库(EMBASE)、护理学与健康领域数据库(CINAHL)、美国国立医学图书馆生物医学数据库(PubMed)以及国家研究注册库。我们查阅了所有文章的参考文献列表,并联系该领域专家以确定符合条件的试验。我们还联系了脊柱固定设备制造商以获取信息。
比较疑似脊髓损伤的创伤患者脊柱固定策略的随机对照试验。排除健康志愿者的试验。
两名评价员独立将入选标准应用于试验报告并提取数据。
我们未找到关于创伤患者脊柱固定策略的随机对照试验。
我们未找到任何符合纳入标准的随机对照试验。脊柱固定对创伤患者死亡率、神经损伤、脊柱稳定性及不良反应的影响仍不确定。由于气道梗阻是创伤患者可预防死亡的主要原因,且脊柱固定,尤其是颈椎固定,可能导致气道受压,因此不能排除固定可能增加死亡率和发病率的可能性。需要大型前瞻性研究来验证脊柱损伤高风险创伤患者脊柱固定的决策标准。需要在创伤患者中进行随机对照试验,以确定脊柱固定替代策略的相对有效性。