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[子宫颈原发性恶性黑色素瘤:附1例报告并文献复习]

[Primary malignant melanoma of the cervix uteri: apropos of 1 case with review of the literature].

作者信息

Zamiati S, Sahraoui S, Jabri L, Louahlia S, Sqalli S, Kahlain A

机构信息

Laboratoire d'anatomie pathologique, CHU Ibn Rochd, quartier des hôpitaux, Casablanca, Maroc.

出版信息

Gynecol Obstet Fertil. 2001 May;29(5):381-5. doi: 10.1016/s1297-9589(01)00148-5.

Abstract

The authors report a case of malignant melanoma of the cervix uteri diagnosed in a young 35-year-old patient. Isolated genital bleeding was the beginning symptom. The physical exam showed a cervical dark tumor, with extension into the vagina (superior third), the parametrium was free. Cervical biopsy concluded to a malignant melanoma. No other abnormalities were observed and the tumor was classed stage IIA-FIGO. A total hysterectomy with bilateral annexectomy and pelvic lymphadenectomy was performed. In the way, the patient died after ten months by local and general recurrence. Primitive malignant melanoma of the cervix uteri is rare. Only 39 cases are reported in literature at this day. It is usually initially misdiagnosed mainly in the achromic forms, then the immuno-histochemical study is useful. Its treatment is not well codified and its histogenesis was controversial for a long time.

摘要

作者报告了一例在一名35岁年轻患者中诊断出的子宫颈恶性黑色素瘤病例。孤立性生殖器出血是首发症状。体格检查显示宫颈有一个深色肿瘤,延伸至阴道(上三分之一),宫旁组织未受累。宫颈活检确诊为恶性黑色素瘤。未观察到其他异常,肿瘤被分类为FIGO IIA期。进行了全子宫切除术、双侧附件切除术和盆腔淋巴结清扫术。在此过程中,患者在十个月后因局部和全身复发死亡。原发性子宫颈恶性黑色素瘤很罕见。目前文献中仅报道了39例。它通常最初主要在无色型中被误诊,随后免疫组织化学研究很有用。其治疗方法尚未很好地规范,并且其组织发生长期存在争议。

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