Matsushita H, Kurabayashi T, Tomita M, Yamamoto Y, Aoki Y, Tanaka K
Department of Obstetrics and Gynecology, Niigata University School of Medicine, Niigata, Japan.
Gynecol Obstet Invest. 2001;51(4):274-6. doi: 10.1159/000058064.
Ovarian carcinoma usually presents in an indolent manner. A patient with ovarian cancer rarely shows acute clinical features which require immediate medical intervention.
We present a 36-year-old Japanese woman with an ovarian tumor, who suffered general fatigue and increased abdominal girth on admission. Her hemoglobin, platelet count and fibrinogen were decreased, and fibrin/fibrinogen degradation products were elevated, which determined the diagnosis of disseminated intravascular coagulation (DIC). Since computed tomography scan and magnetic resonance imaging revealed an intratumoral hemorrhage, an emergency laparotomy was performed. The patient was found to have ovarian cancer with a massive intratumoral hemorrhage, and DIC improved immediately after the operation.
The clinician should be alert to the possibility that intratumoral bleeding of ovarian cancer might be associated with DIC.
卵巢癌通常呈隐匿性发病。卵巢癌患者很少表现出需要立即进行医学干预的急性临床特征。
我们报告一名36岁患有卵巢肿瘤的日本女性，入院时出现全身乏力和腹围增加。她的血红蛋白、血小板计数和纤维蛋白原降低，纤维蛋白/纤维蛋白原降解产物升高，据此诊断为弥散性血管内凝血（DIC）。由于计算机断层扫描和磁共振成像显示肿瘤内出血，遂进行了急诊剖腹手术。发现该患者患有卵巢癌并伴有大量肿瘤内出血，术后DIC立即得到改善。
临床医生应警惕卵巢癌肿瘤内出血可能与DIC相关的可能性。
