Le Faou A, Guy I, Riou J Y
Ann Dermatol Venereol. 1979 Mar;106(3):267-72.
We have studied 386 strains of Neisseria gonorrhoeae isolated in our laboratory from July 1977 to October 1978, with the Catlin's auxotyping method. The distribution of the four main auxotypes, i. e. (+), (PRO-), (ARG-), (ARG-, HYX-, URA-), is different from those reported by others (in U. S. A. and Sweden). In Strasbourg, the auxotype (+) is prevalent. We have noticed some differences among classes of population. For example (ARG-) and (ARG-, HYX-, URA-) are scarcely isolated from prostitutes and we have found less (ARG-) strains in women than in men. The determination of the minimum inhibitory concentration of 6 antibiotics has shown there was no differences between the auxotypes except for the (ARG-, HYX-, URA-) strains which are more susceptible to all the antibiotics, but spectinomycin. Since August 1978, we have also noticed an increasing of the resistance which is mainly due to (PRO-) strains.
我们用卡特林辅助分型法研究了1977年7月至1978年10月间在我们实验室分离出的386株淋病奈瑟菌。四种主要辅助型,即(+)、(脯氨酸-)、(精氨酸-)、(精氨酸-、组氨酸-、尿嘧啶-)的分布与其他国家(美国和瑞典)报道的不同。在斯特拉斯堡,(+)辅助型较为普遍。我们注意到不同人群类别之间存在一些差异。例如,(精氨酸-)和(精氨酸-、组氨酸-、尿嘧啶-)很少从妓女中分离出来,而且我们发现女性中的(精氨酸-)菌株比男性少。对6种抗生素的最低抑菌浓度的测定表明,除了(精氨酸-、组氨酸-、尿嘧啶-)菌株对所有抗生素(除壮观霉素外)更敏感外,各辅助型之间没有差异。自1978年8月以来,我们还注意到耐药性在增加,这主要归因于(脯氨酸-)菌株。