Taussky D, Cserhati M, Pescia R
Department of Radiotherapy, Triemli Hospital, Zürich, Switzerland.
Arch Orthop Trauma Surg. 2001 May;121(5):271-3. doi: 10.1007/s004020000223.
Twenty-seven consecutive patients at high risk of developing heterotopic ossifications (HO) after implantation of a hydroxyapatite (HA)-coated hip prosthesis were irradiated with a single dose of 7 Gy, at least 4 h before the operation. The femoral stem was not shielded during radiotherapy (RT). After a median follow-up of 14.8 months, no clinically significant HO could be found, while 12 (52%) patients in this high-risk population had only minor HO (grade I). No reoperation was needed, and no evidence of prosthesis migration was observed. We conclude that single-dose, preoperative RT for HA-coated hip prosthesis can effectively inhibit HO. Not blocking the femoral stem does not result in prosthesis migration.
27例在植入羟基磷灰石（HA）涂层髋关节假体后有发生异位骨化（HO）高风险的连续患者，在手术前至少4小时接受了单次7 Gy的照射。放疗（RT）期间未对股骨干进行屏蔽。中位随访14.8个月后，未发现有临床意义的HO，而该高风险人群中有12例（52%）患者仅有轻微HO（I级）。无需再次手术，也未观察到假体移位的证据。我们得出结论，HA涂层髋关节假体术前单次放疗可有效抑制HO。不屏蔽股骨干不会导致假体移位。
