Schröder T, Nolte M, Kox W J, Spies C
Klinik für Anästhesiologie und operative Intensivmedizin, Charité, Campus Mitte, Humboldt-Universität zu Berlin.
Herz. 2001 May;26(3):222-8. doi: 10.1007/pl00002024.
Approximately 1-2% of all anesthetized patients are morbidly obese (body mass index > 35 kg/m2). The perioperative mortality is significantly elevated (up to 20%) compared with lean patients. Morbidly obese patients are at high risk for cardiopulmonary dysfunction. Difficult airway management is reported in 13-20% of obese patients. Hypoxia is often observed due to faster desaturation during induction of anesthesia. After surgery, patients are endangered by a high incidence of obstructive sleep apnea syndrome (50%), pulmonary atelectasis (5%) and acute pulmonary embolism (5-12%).
Individualized perioperative management is required based on preoperative history and physical examination. Modern anesthetic drugs (desfluran, sevoflurane or propofol, and remifentanil, respectively) allow rapid recovery and early postoperative mobilization. Adequate monitoring, e.g. by an intraarterial blood pressure monitoring and repetitive blood gas analyses, improves patient safety prior the onset of complications.
Postoperative admission on an intensive care unit of morbidly obese patients is based upon concomitant diseases and surgical requirements. The main reason for admission is an inadequate pulmonary gas exchange. This interdisciplinary approach will reduce the risk of anesthesia and avoid complications in morbidly obese patients.
在所有接受麻醉的患者中,约1%-2%为病态肥胖(体重指数>35kg/m²)。与体型偏瘦的患者相比,围手术期死亡率显著升高(高达20%)。病态肥胖患者存在心肺功能障碍的高风险。据报道,13%-20%的肥胖患者存在气道管理困难。由于麻醉诱导期间去饱和更快,常观察到低氧血症。术后,患者面临阻塞性睡眠呼吸暂停综合征(50%)、肺不张(5%)和急性肺栓塞(5%-12%)的高发病率风险。
需要根据术前病史和体格检查进行个体化的围手术期管理。现代麻醉药物(分别为地氟烷、七氟烷或丙泊酚以及瑞芬太尼)可实现快速恢复和术后早期活动。充分的监测,如通过动脉内血压监测和重复血气分析,可在并发症发生前提高患者安全性。
病态肥胖患者术后入住重症监护病房取决于伴发疾病和手术需求。入住的主要原因是肺气体交换不足。这种多学科方法将降低麻醉风险并避免病态肥胖患者出现并发症。