Traini T, Murmura G, Giammaria G, Ciavarelli L, Caputi S
Dipartimento di Scienze Odontostomatologiche, Cattedra di Malattie Odontostomatologiche, Università degli Studi G. d Annunzio, Chieti, Italy.
Minerva Stomatol. 2001 May;50(5):173-80.
The salivary calculus is an ancient pathologic condition, called sublingual stone by Hyppocrates. It is well-defined from a anatomo-pathologic, diagnostic and topographic viewpoint, though some pathogenesis-related doubts still exist. This work aims at relating the micro-morpho-structural aspect of a salivary calculus of remarkable dimensions with the current calculogenetic hypotheses.
A 1.1 g salivary calculus removed from the initial section of Wrthon s duct in the right-hand submandibular gland of a 42 year old male has been studied. Following the fixation in 4% buffered formalin and the inclusion in resin, it was serially sectioned in 15-20 micron slices. Some sections were coloured with toluidine blue O and acid fuchsin. The exeresis of the calculus was carried out intraorally, with marsupialization under local anesthesia. The analysis was performed using a SEM with backscattered electrons and a polarised and transmitted light microscope.
The investigations have outlined the presence of various organic cores and a concentric, stratiform architecture interrupted by radial elements.
The formation of this calculus may be due to mixed secondary lithiasis resulting from the formation of colloids and crystalloids.
涎石病是一种古老的病理状况，希波克拉底称之为舌下结石。从解剖病理学、诊断学和局部解剖学角度来看，其定义明确，尽管在发病机制方面仍存在一些疑问。这项工作旨在将一个尺寸较大的涎石的微观形态结构方面与当前的结石形成假说联系起来。
对从一名42岁男性右侧下颌下腺沃顿管起始段取出的一块1.1克涎石进行了研究。在4%缓冲福尔马林中固定并包埋于树脂后，将其切成15 - 20微米厚的连续切片。一些切片用甲苯胺蓝O和酸性品红染色。结石摘除在局部麻醉下经口腔行袋形缝合术进行。使用带有背散射电子的扫描电子显微镜以及偏振光和透射光显微镜进行分析。
研究揭示了存在各种有机核心以及由径向元素中断的同心层状结构。
这块结石的形成可能是由于胶体和晶体形成导致的混合性继发性结石病。
