Wells D, Delhanty J D
UCL Centre for Preimplantation Genetic Diagnosis, Dept of Obstetrics and Gynaecology, University College London, 86-96 Chenies Mews, London, UK WC1E 6HX.
Trends Mol Med. 2001 Jan;7(1):23-30. doi: 10.1016/s1471-4914(00)01867-0.
Preimplantation genetic diagnosis is an alternative to prenatal diagnosis for the detection of genetic disorders. Tests are conducted on single cells biopsied from embryos before they are implanted, allowing the selection of unaffected embryos before a pregnancy has been established. Thus, the issue of pregnancy termination is circumvented. The use of preimplantation genetic diagnosis might have a significant impact on in vitro fertilization success rates as well as allowing the diagnosis of inherited disease.
植入前基因诊断是一种用于检测遗传疾病的产前诊断替代方法。在胚胎植入前，对从胚胎中活检的单个细胞进行检测，从而在确定妊娠之前选择未受影响的胚胎。因此，避免了终止妊娠的问题。植入前基因诊断的应用可能会对体外受精成功率产生重大影响，同时也能实现对遗传性疾病的诊断。
