Larsen T K, Qvist N, Bak M
Departments of Surgical Gastroenterology and Pathology, Odense University Hospital, Odense, Denmark.
J Pediatr Surg. 2001 Jul;36(7):1066-7. doi: 10.1053/jpsu.2001.24754.
Neutropenic enterocolitis (NE) is a clinicopathologic condition characterized by bowel wall inflammation, which can proceed to necrosis and perforation. It is mostly seen in neutropenic patients with leukemia who undergo induction treatment with chemotherapy. Most often the cecum is involved. The authors present a 12-year-old girl with acute lymphocytic leukemia who, under maintenance therapy, experienced NE. The disease was localized to the left side of colon, and even the rectum was involved, which is an unusual localization of the disease. An ileoanal anastomosis with a J-pouch was done in a second operation with a good outcome.
中性粒细胞减少性小肠结肠炎(NE)是一种以肠壁炎症为特征的临床病理状态,可发展为坏死和穿孔。它多见于接受化疗诱导治疗的白血病中性粒细胞减少患者。最常累及盲肠。作者报告了一名12岁患急性淋巴细胞白血病的女孩,在维持治疗期间发生了NE。病变局限于结肠左侧,甚至直肠也受累,这是该疾病不常见的部位。第二次手术进行了带J型贮袋的回肠肛管吻合术,效果良好。